LP3 Network Free Webinar - Veterinary Compounding, A Customized Approach

Download in electronic PDF format for $25



Search the Complete Journal Archives

Basics of Compounding: Basics of Compounding with Esters

Author(s):  Allen Loyd V Jr

Issue:  Sep/Oct 2010 - Supporting Quality Pharmaceutical Compounding World Wide
View All Articles in Issue

Abstract:  Pharmacists involved in compounding must consider a number of factors when determining the actual quantity of an active ingredient to use for a compounded prescription. Is the drug being dosed as its base form or as a salt, ester, etc.? Since the bulk substance, or active pharmaceutical ingredient, is not 100% active drug in all cases, then it is important to know whether or not the dose of the drug is based upon the drug ester or drug base form. This article discusses the basics of compounding with those drugs that are esters by the addition of a moiety that will form an ester for certain purposes.

Related Keywords: Loyd V. Allen, Jr., PhD, RPh, esters, solubility, prodrugs

Related Categories: SUPPORT, QUALITY CONTROL, UNITED STATES PHARMACOPEIA CONVENTIONS

Printer-Friendly Version

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Rapid-Dissolve Technology: An Interview With Loyd V. Allen, Jr., PhD, RPh Allen Loyd V Jr Nov/Dec 2003 449-450 Buy
Basics of Compounding: Basics of Compounding with Esters Allen Loyd V Jr Sep/Oct 2010 416-418 Buy
Sorbitan Esters, Featured Excipient: Allen Loyd V Jr May/Jun 2002 221-223 Buy
Mesna 20-mg/mL Syrup Allen Loyd V Jr May/Jun 2006 224 Buy
Basics of Compounding for the Treatment of Warts Allen Loyd V Jr Mar/Apr 2004 126 Buy
Physico-chemical Stability of MabThera Drug-product Solution for Subcutaneous Injection under In-use Conditions with Different Administration Materials Mueller Claudia, Dietel Elde, Heynen Severin R, Nalenz Heiko, Goldbach Pierre, Mahler Hanns-Christian, Schmidt Johannes, Grauschopf Ulla, Schoenhammer Karin May/Jun 2015 261-267 Buy
Basics of Compounding: Clinical Pharmaceutics, Part 1 Allen Loyd V Jr Sep/Oct 2016 389-396 Buy
Hygrometers and Thermohygrometers: Environmental Monitoring Ensures the Potency and Stability of Compounding Agents Allen Loyd V Jr, McKenzie Robert, Ainsworth Ron, Kastango Eric S, Kaestner Rick, Rebelo Andre, Burnside Paul, Schultz Gerald Jul/Aug 2010 284-300 Buy
Basics of Compounding: Basics of Compounding with Organic Salts Allen Loyd V Jr Jul/Aug 2010 322-326 Buy
Basics of Compounding: Basics of Compounding with Inorganic Salts Allen Loyd V Jr Mar/Apr 2011 146-153 Buy