Download in electronic PDF format for $35

Search the Complete Journal Archives

Considerations for Percutaneous Absorption

Author(s):  Newton Stephen J, Cook Jennifer M

Issue:  Jul/Aug 2010 - Sterile Compounding
View All Articles in Issue

Abstract:  Percutaneous absorption is affected by numerous factors. Whether they are internal or external factors, the compounding pharmacist must collectively consider these variables in order to provide a safe and effective topical preparation for the patient. By considering the physiochemical and dermal factors that affect percutaneous absorption of a medication, an effective topical medication can be formulated to treat the patient’s specific indication. Furthermore, this article will review the background information necessary to formulate transdermal prescriptions for their patients.

Related Keywords: Stephen J. Newton, RPh, Jennifer M. Cook, PharmD, percutaneous absorption, topical preparations, transdermal administration, skin hydration, skin damage, dermal lipids, pluronic solubility, formulation, solid lipid nanoparticles, particle size, partition coefficient


Printer-Friendly Version

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Considerations for Percutaneous Absorption Newton Stephen J, Cook Jennifer M Jul/Aug 2010 301-304 Buy
Veterinary Transdermal Medications: A to Z Davidson Gigi S Mar/Apr 2003 106 Buy
In Vitro Skin Penetration and Skin Content of Progesterone from Various Topical Formulations Heustess Allie, Asbill Scott, Eagerton David, Arnold John Nov/Dec 2014 512-515 Buy
Evaluation of Percutaneous Absorption Performance for Human Female Sexual Steroids into Pentravan Cream Polonini Hudson C, Brandão Marcos Antônio F, Ferreira Anderson O, Ramos Cristiano, Raposo Nádia R B Jul/Aug 2014 332-340 Buy
Basics of Compounding for Dry-Skin Conditions Allen Loyd V Jr Nov/Dec 2003 460-463 View Sample
Basics of Compounding–Nonsterile: Compounding Self-emulsifying Drug Delivery Systems and Other Self-emulsifying Lipid Formulations, Part 1 Allen Loyd V Jr May/Jun 2018 220-228 Buy
Basics of Compounding--Nonsterile: Compounding Self-emulsifying Drug Delivery Systems and Other Self-emulsifying Lipid Formulations, Part 2 Allen Loyd V Jr Jul/Aug 2018 294-300 Buy
Skin Penetration and Antinociception of Topical Gabapentin Formulations Bryson Evan, Asbill Scott, Sweitzer Sarah Nov/Dec 2014 504-511 Buy
Preparation and In Vitro Evaluation of a Pluronic Lecithin Organogel Containing Ricinoleic Acid for Transdermal Delivery Boddu Sai HS, Bonam Sindhu Prabha, Wei Yangjie, Alexander Kenneth May/Jun 2014 256-261 Buy
Chemical Penetration Enhancers Newton Stephen J Sep/Oct 2013 370-374 Buy