Download in electronic PDF format for $25

Search the Complete Journal Archives

Particulates in Parenterals

Author(s):  Allen Loyd V Jr

Issue:  Jan/Feb 2000 - Compounding for Pain Management
View All Articles in Issue

Abstract:  Particulates can be entrapped in the lungs, liver and spleen, and particles greater than 7 microns in diameter are threatening. In this brief discussion, the author covers sources of particulates and their detection. He ends by cautioning that pharmacists who do not have the necessary training, facilities and equipment should not be involved in sterile-products compounding; and that they should be familiar with the United States Pharmacopeia/National Formulary guidelines on the preparation of sterile products, in addition to other organizations’ guidelines.

Related Keywords: environmental contaminants, filter, glass particles, Microscopic Particle Count Test, packaging components, parenteral products, particulate contamination, particulates, precipitates, solvent impurities, sterile products compounding, trace contaminants


Printer-Friendly Version

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Particulates in Parenterals Allen Loyd V Jr Jan/Feb 2000 43 Buy
Basics of Sterile Compounding: Particulate Matter Akers Michael J Sep/Oct 2017 395-404 Buy
Sterile Filtration Akers Michael J Sep/Oct 2015 393-401 Buy
Microbiologic Testing for 503A Sterile-Compounding Pharmacies Mixon William, Roth Abby May/Jun 2017 193-203 Buy
Quality Assurance for Sterile Products Kastango Eric S, Douglass Kate Jul/Aug 2001 246 Buy
Autoclaves for the Sterilization of Compounded Parenteral Products Rahe Hank Mar/Apr 2003 114 Buy
Standard Operating Procedure for Particulate Testing for Sterile Products Allen Loyd V Jr Jan/Feb 1998 78 Buy
Adventures in the Environmental World and Environmental Microbiology Sampling of Air for Pharmaceutical Sterile Compounding Ligugnana Roberto May/Jun 2017 182-190 Buy
Basics of Sterile Compounding: Sterile Product Packaging and Delivery Systems Akers Michael J Nov/Dec 2015 491-500 Buy
Basics of Sterile Compounding: Contamination Control Akers Michael J May/Jun 2015 232-238 Buy