LP3 Network Free Webinar - Veterinary Compounding, A Customized Approach

Download in electronic PDF format for $25



Search the Complete Journal Archives

Stability of Ephedrine Sulfate at Ambient Temperature and 4°C in Polypropylene Syringes

Author(s):  Storms Meredith L, Stewart James T, Warren Flynn W

Issue:  Sep/Oct 2001 - Bioidentical Hormone Replacement Therapy
View All Articles in Issue

Abstract:  The stability of 5 mg/mL ephedrine sulfate in 0.9% sodium chloride in 10-mL polypropylene syringes stored at ambient temperature and at 4°C for up to 60 days was investigated. Concentration levels of ephedrine sulfate were determined by means of a high-performance liquid chromatography stability-indicating assay at 0, 1, 4, 7, 14, 30, 45, and 60 days after preparation of the syringes. Benzyl alcohol, which was added as a preservative, did not interfere with the assay. The injections in polypropylene syringes were stable for up to 60 days at both ambient temperature and at 4°C. The pH of the ephedrine sulfate injections did not change appreciably in a particular direction during the 60-day study period. These data support the stability of ephedrine sulfate under the storage conditions investigated in this study.

Related Keywords: Ephedrine sulfate, stability of

Related Categories: INFUSION, PEER-REVIEWED, STABILITIES, COMPATIBILITIES

Printer-Friendly Version

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Stability of Ephedrine Sulfate at Ambient Temperature and 4°C in Polypropylene Syringes Storms Meredith L, Stewart James T, Warren Flynn W Sep/Oct 2001 394-396 Buy
Physical and Chemical Stability of Low and High Concentrations of Morphine Sulfate with Clonidine Hydrochloride Packaged in Plastic Syringes Xu Quanyun A, Trissel Lawrence A, Pham Lien Jan/Feb 2002 66-69 Buy
Physical and Chemical Stability of Low and High Concentrations of Morphine Sulfate with Bupivacaine Hydrochloride Packaged in Plastic Syringes Trissel Lawrence A, Xu Quanyun A, Pham Lien Jan/Feb 2002 70-73 Buy
Stability of Gentamicin Sulfate and Tobramycin Sulfate in AutoDose Infusion System Bags Xu Quanyun A, Trissel Lawrence A, Saenz Christopher A, Ingram Delshalonda S Mar/Apr 2002 152-154 Buy
Compatibility and Stability of Potassium Chloride and Magnesium Sulfate in 0.9% Sodium Chloride Injection and 5% Dextrose Injection Solutions Quay Irene, Tan Edward Jul/Aug 2001 323-324 Buy
Ephedrine Sulfate 50-mg/mL Injection Allen Loyd V Jr Sep/Oct 2014 411 Buy
Compatibility and Stability of Linezolid Injection Admixed with Gentamicin Sulfate and Tobramycin Sulfate Xu Quanyun A, Trissel Lawrence A, Zhang Yanping, Williams Kimberly Y Nov/Dec 2000 476-479 Buy
Physical and Chemical Stability of Morphine Sulfate 5-mg/mL and 50-mg/mL Packaged in Plastic Syringes Trissel Lawrence A, Xu Quanyun A, Pham Lien Jan/Feb 2002 62-65 Buy
Stability of Amikacin Sulfate in AutoDose Infusion System Bags Zhang Yanping, Trissel Lawrence A May/Jun 2003 230-232 Buy
In Vitro Studies on the Release of Morphine Sulfate from Compounded Slow-Release Morphine-Sulfate Capsules Webster Kathy D, Al-Achi Antoine, Greenwood Robert Sep/Oct 1999 409-411 Buy