Download in electronic PDF format for $35



Search the Complete Journal Archives

Contamination Control in Compounding Areas

Author(s):  Mulder Kyle, Gonzales Ben A

Issue:  Jul/Aug 2019 - Volume 23, Number 4
View All Articles in Issue

Abstract:  In pharmaceutical compounding, effective contamination control is based on a complete understanding of the impact, sources, mechanisms, and prevention of adulterants in the compounding suite. Only then do the multiple facets of designing, constructing, maintaining, cleaning, using, and monitoring controlled environments make sense. This article presents an overview of the types of contaminants likely to compromise the potency and for their eradication. The information provided also applies to the contamination of other sites such as surgery suites, hallways, bathrooms, and the home setting. In a series of upcoming articles, the importance of compounding techniques, primary and secondary engineering controls, personal protective equipment, environmental monitoring, cleaning processes, hazardous-drug considerations, and certification of the compounding suite will be discussed in detail.

Related Keywords: Kyle Mulder, NSF, CETA RCCP-SCF, NEBB CPT CP, drug contamination prevention, contaminants, adulterants, environmental controls, compounded sterile preparations, drug safety, drug purity, hazardous drugs, heat, humidity, weather, water, light, sound, vibration, static electricity, chemical contaminants, physical contaminants, environmental contaminants, vapors, air quality, gases, airflow, particulates, decontamination, air filtration, air filters, insanitary conditions, ISO Class 5 area, personnel, staff training

Related Categories: ENVIRONMENTAL , QUALITY CONTROL

Printer-Friendly Version

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Contamination Control in Compounding Areas Mulder Kyle, Gonzales Ben A Jul/Aug 2019 271-278 Buy
Certification of Powder-containment Hoods for Nonsterile Compounding Mulder Kyle, Dozzi Raphael Sep/Oct 2018 369-384 Buy
Basics of Compounding for Hazardous Drugs, Part 2: Regulation and Sources of Contamination Allen Loyd V Jr Nov/Dec 2006 446-448 Buy
Compounding Enclosures: Ensuring Safety During the Preparation of Sterile and Nonsterile Formulations Ashe Krystina, Baskett Dustin Sep/Oct 2018 387-398 Buy
PostScription: Drug Disposal: Compounding Pharmacists' Involvement in the Prevention of Prescription Drug Misuse and Abuse Williams LaVonn A Nov/Dec 2011 526-527 Buy
PreScription: 2017 Pharmacy Compounding Issues: The U.S. Food and Drug Administration, Harzardous Drugs, and Wasted Drugs Allen Loyd V Jr Sep/Oct 2017 356 Buy
How to Develop and Maintain a Hazardous Drug List Dillon L Rad May/Jun 2019 182-186 Buy
Does Your Drug Expertise Include Clinical Pharmaceutics? Newton David W May/Jun 2016 202-206 Buy
Roboticized Compounding of Oncology Drugs in a Hospital Pharmacy Palma Elisabetta, Bufarini Celestino Sep/Oct 2014 358-364 Buy
Drug Shortage Compounding: The Only Safe Medication Source in a Time of Crisis Lyon Joanna Nov/Dec 2012 456-460 Buy