Download in electronic PDF format for $25

Kalchem International - Chemicals and Compounding Supplies

Search the Complete Journal Archives

Case Study: Absorption of Testosterone Cream via Scrotal Delivery

Author(s):  Needham Shawn, Needham Shane

Issue:  Nov/Dec 2018 - Volume 22, Number 6
View All Articles in Issue

Abstract:  Transdermal testosterone has been used for years to treat patients with low testosterone symptoms. Clinically, we have monitored patients to evaluate results of testosterone absorption via blood serum concentrations. The data on multiple time points to determine trough and peak concentrations is lacking in the literature. In this case study, we demonstrate the absorption of testosterone cream via scrotal delivery. The data suggests that after application therapeutic levels are reached with concentrations of (1204.7 ng/dL) within two hours. Additionally, consistent concentrations (1320.6 ng/dL) remain beyond six hours. To our knowledge, this is the first study to collect and measure multiple time points for testosterone via transdermal delivery. The research indicates that testosterone via transdermal delivery is an excellent method to achieve therapeutic concentrations of testosterone. Most importantly, the patient’s symptoms resolved without side effects.

Related Keywords: Shawn Needham, BS Pharmacy, RPh, Shane Needham, PhD Analytical Chemistry, testosterone cream, scrotal delivery, transdermal administration, case study, topical testosterone cream, low testosterone symptoms, decreased libido, erectile dysfunction, lethary, loss of lean body mass, weight gain

Related Categories: CASE REPORTS, DOSAGE FORMS/DRUG CARRIERS, ENDOCRINOLOGY/HORMONES/ MENOPAUSE/ANDROPAUSE, UROLOGY/URINARY TRACT

Printer-Friendly Version

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Case Study: Absorption of Testosterone Cream via Scrotal Delivery Needham Shawn, Needham Shane Nov/Dec 2018 466-468 Buy
Veterinary Transdermal Medications: A to Z Davidson Gigi S Mar/Apr 2003 106 Buy
Compounded Testosterone Gels: A Guide for Clinicians and Pharmacists Cutter Christopher B Nov/Dec 2000 432 View Sample
Hormone Treatment Options for Males: What to Do for Men with Low Testosterone Biundo Bruce Jul/Aug 2009 276-279 Buy
Aminophylline 3%, Co-dergocrine Mesylate 0.05%, and Isosorbide Dinitrate 0.25% Cream for the Treatment of Orgasmic Dysfunction in Women Mason Dave Jul/Aug 2002 255-256 Buy
Tri-Est, Progesterone, and Testosterone in Versatile, Phytobase, Fitaline, and HRT Supreme Cream Bases Allen Loyd V Jr May/Jun 2017 238 Buy
In Vitro Percutaneous Absorption of Ketoprofen and Testosterone: Comparison of Pluronic Lecithin Organogel vs. Pentravan Cream Lehman Paul A, Raney Sam G May/Jun 2012 248-252 Buy
An Academic Practice Partnership: An Innovative Course in Advanced Compounding Hale Katherine S, Hammer Dana P, Needham Shawn, Lawhorn Michelle Gaster Jan/Feb 2010 48-53 Buy
Compounded Testosterone Troches to optimize Health and the Testosterone Controversy Guth Michael AS May/Jun 2015 195-203 Buy
Testosterone Deficiency in Men: New Treatments for Andropause Biundo Bruce, Shippen Eugene Nov/Dec 2000 429 Buy