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Basics of Compounding: Compounding Irrigation Solutions for Sterile and Nonsterile Preparations

Author(s):  Allen Loyd V Jr

Issue:  Nov/Dec 2017 - Volume 21, Number 6
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Abstract:  Compounding pharmacists are sometimes called upon to prepare irrigation solutions, especially in the hospital or clinical setting. Irrigations are indicated for washing or bathing surgical incisions, wounds, and body tissues, including body cavities. Some irrigation solutions coming in contact with exposed tissue, must meet stringent requirements of sterility and bacterial endotoxins. Compounded irrigation solutions may involve wound(s), the bladder, and also may be for ophthalmic, otic, and nasal application. Some vaginal douches/instillations and rectal solutions may also be used as irrigations. As with any medication administered to the body or used on body tissues, there are requirements, and these may vary depending on the type of irrigation solution involved.

Related Keywords: Loyd V. Allen, Jr., PhD, RPh, formulations, irrigation solutions, compounded sterile preparations, wound irrigation solutions, bladder irrigation solutions, ophthalmic irrigation solutions, nasal irrigation solutions, otic irrigation solutions, commercial irrigation solutions, physiochemical properties

Related Categories: EAR NOSE THROAT, FORMULATIONS, OPHTHALMICS, QUALITY CONTROL, WOUND CARE, UROLOGY/URINARY TRACT

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