Download in electronic PDF format for $35



Search the Complete Journal Archives

Menopausal Symptom Relief and Side Effects Experienced by Women Using Compounded Bioidentical Hormone Replacement Therapy and Synthetic Conjugated Equine Estrogen and/or Progestin Hormone Replacement Therapy, Part 3

Author(s):  Deleruyelle Laura J

Issue:  Jan/Feb 2017 - Volume 21, Number 1
View All Articles in Issue

Abstract:  The use of compounded bioidentical hormone replacement therapy by menopausal women has become a popular alternative to traditional synthetic conjugated equine estrogen and progestin hormone replacement therapy due to safety concerns raised by recent studies. However, due to the lack of randomized, large-scale trials to evaluate the efficacy and side-effect profile of compounded bioidentical hormone replacement therapy many healthcare providers are reluctant to prescribe such therapy. The purpose of this study was to compare women’s menopausal symptom relief and side effects experienced when using compounded bioidentical hormone replacement therapy and traditional hormone replacement therapy. A descriptive comparative design was used. Inferential and descriptive statistical procedures including a paired difference t-test, two-sample t-test, and f-tests (percentage, mean, standard deviation, frequency) were run on the Statistical Package for the Social Sciences. The framework used to guide this study was Lenz and Pugh’s Theory of Unpleasant Symptoms. Surveys were distributed once to a convenient sample of women aged 35 and older when they dropped off or picked up their prescriptions at a pharmacy. Of the 216 surveys distributed, 70 were returned from those women taking compounded bioidentical hormone replacement therapy and 53 from traditional hormone replacement therapy. The survey contained 15 questions pertaining to age, duration of hormone replacement therapy, type and formulation of hormone replacement therapy, reasons for initiating hormone replacement therapy, symptoms before and one month after hormone replacement therapy, and side effects related to hormone replacement therapy. Included in part 1 of this series of articles was the introduction to the study conducted and the results of the literature review that was conducted for the purpose of examining the current data related to the topic of hormone replacement therapy. Part 2 provided a brief discussion on the significance of this study to nursing and provided the methods used in this study. The results and conclusion of this study are provided within this article.

Related Keywords: Laura J. Deleruyelle, DNP, MSN, FNP-BC, ABAAHP, menopause, adverse effects, bioidentical hormone replacement therapy, BHRT, climacteric, Theory of Unpleasant Symptoms, survey research, dosage forms, routes of administration, side effects, conjugated equine estrogen, progestin, nursing practice

Related Categories: HRT, MENTAL HEALTH, ADVERSE DRUG EVENTS, ALTERNATIVE/COMPLEMENTARY THERAPIES, ENDOCRINOLOGY/HORMONES/ MENOPAUSE/ANDROPAUSE, NURSING

Printer-Friendly Version

Related Articles from IJPC
Title (Click for Abstract / Details) Author Issue Page View/Buy
Menopausal Symptom Relief and Side Effects Experienced by Women Using Compounded Bioidentical Hormone Replacement Therapy and Synthetic Conjugated Equine Estrogen and/or Progestin Hormone Replacement Therapy, Part 3 Deleruyelle Laura J Jan/Feb 2017 6-16 Buy
Menopausal Symptom Relief and Side Effects Experienced by Women Using Bioidentical Hormone Replacement Therapy and Synthetic Conjugated Equine Estrogen and/or Progestin Hormone Replacement Therapy, Part 1 Deleruyelle Laura J Sep/Oct 2016 359-364 Buy
Menopausal Symptom Relief and Side Effects Experienced by Women Using Compounded Bioidentical Hormone Replacement Therapy and Synthetic Conjugated Equine Estrogen and/or Progestin Hormone Replacement Therapy, Part 2 Deleruyelle Laura J Nov/Dec 2016 447-454 Buy
The Science Behind Hormone Replacement Therapy, Part 1 Wepfer Scott T Nov/Dec 2001 462-464 Buy
Bioidentical Hormone Replacement Therapy, Part 3, A Review of Wepfer Scott T Mar/Apr 2002 142-146 Buy
The Effects of Compounded Bioidentical Transdermal Hormone Therapy on Hemostatic, Inflammatory, and Immune Factors; Cardiovascular Biomarkers; Quality of Life Measures; and Health Outcomes in Perimenopausal and Postmenopausal Women Stephenson Kenna, Neuenschwander Pierre F, Kurdowska Anna K Jan/Feb 2013 74-85 View Sample
Hormone Replacement Therapy: Part 1 - The Evolution of Hormone Treatment Lorentzen Jean Sep/Oct 2001 336-338 Buy
A Perspective on HRT for Women: Picking Up the Pieces After the Women's Health Initiative Trial - Part 1 Gillson George R, Zava David T Jul/Aug 2003 250-256 Buy
Bioidentical Hormones in the Treatment of Osteoporosis Boomsma Diane Sep/Oct 2001 339-341 Buy
Natural Hormone Replacement Therapy: What It Is and What Consumers Really Want Reed-Kane Dana Sep/Oct 2001 332-335 View Sample