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Basics of Compounding: Clinical Pharmaceutics, Part 2

Author(s):  Allen Loyd V Jr

Issue:  Nov/Dec 2016 - Volume 20, Number 6
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Abstract:  This article represents part 2 of a 2-part article on the topic of clinical pharmaceutics. Pharmaceutics is relevant far beyond the pharmaceutical industry, compounding, and the laboratory. Pharmaceutics can be used to solve many clinical problems in medication therapy. A pharmacists’ knowledge of the physicochemical aspects of drugs and drug products should help the patient, physician, and healthcare professionals resolve issues in the increasingly complex world of modern medicine. Part 1 of this series of articles discussed incompatibilities which can directly affect a clinical outcome and utilized pharmaceutics case examples of the application and importance of clinical pharmaceutics covering different characteristics. Part 2 continues to illustrate the scientific principles and clinical effects involved in clinical pharmaceutics. Also covered in this article are many of the scientific principles in typical to patient care.

Related Keywords: Loyd V. Allen, Jr., PhD, RPh, topical preparations, transdermal administration, alternative dosage forms, penetration enhancers, occlusive dressings, bioavailability, dose equivalence, drug delivery, compromised skin barrier, skin permeation, thermodynamic effects, supersaturation, parenteral administration, repackaging, infusion, special tubing, adsorption, suppository, excipients, vehicles, clinical outcomes, pharmacy benefits manager, adverse effects, generic drugs, bioequivalence, packaging, storage

Related Categories: EXCIPIENTS, LEGAL, PACKAGING, PARENTERALS, UNITED STATES PHARMACOPEIA CONVENTIONS, DOSAGE FORMS/DRUG CARRIERS

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