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Efficacy and Clinical Value of Commonly Compounded Hormone Replacement Therapy: A Literature Review

Author(s):  Beshay Sarah M,Rivera Gerard,Balthasar Jan,Florea Naomi

Issue:  Jan/Feb 2015 - Volume 19, Number 1
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Abstract:  Hormone replacement therapy compounding is an important practice in the field of pharmacy. The efficacy and clinical value of its use have sometimes been controversial in the current literature. This study focused on providing a summary review of some of the literature regarding clinical and therapeutic value of the commonly used ingredients in hormone replacement therapy compounds, to include progesterone, pregnenolone, estrogen, dehydroepiandrosterone, and testosterone.

Related Keywords: Sarah M. Beshay, Gerard Rivera, PharmD, Jan Balthasar, PharmD, Naomi Florea, PharmD, bioidentical hormone replacement therapy, HRT, steroid hormones, menopause, pregnenolone, progesterone, estriol, estradiol, testosterone, topical preparations, literature review, dehydroepiandrosterone, DHEA, estrogen, transdermal absorption, skin penetration, excipients, dosage forms, clinical efficacy, men, hypogonadism, heart disease, stroke, cholesterol, lipoproteins, sexual function, sexual dysfunction, aging, andropause, insulin, fibrinogen, endometrial hyperplasia

Related Categories: EXCIPIENTS, GERIATRICS, HRT, DOSAGE FORMS/DRUG CARRIERS, ENDOCRINOLOGY/HORMONES/ MENOPAUSE/ANDROPAUSE, LITERATURE REVIEW

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