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Autologous Serum Eye Drops for Severe Dry Eye Syndrome in a Patient with Chronic Graft-vs-Host Disease: A Case Report

Author(s):  Mixon Bill,Mixon Jan,Isbey Edward K III,Sprinkle Shari

Issue:  Sep/Oct 2014 - Volume 18, Number 5
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Abstract:  We present the case of a 49-year-old woman with severe dry eye syndrome caused by chronic graft-versus-host disease that developed after an allogeneic hematopoietic transplant to treat acute myelogenous leukemia. After the use of commercially manufactured products for the treatment of dry eye failed to relieve her photosensitivity, blurred vision, and severe bilateral ocular pain, she benefitted significantly from therapy with compounded autologous serum eye drops. Comments from that patient are included in this report, as are a formulation for the preparation of autologous eye drops and suggestions for their safe and effective use.

Related Keywords: Bill Mixon, RPh, Jan Mixon, RN, Edward K. Isbey III, MD, FAAO, Shari Sprinkle, allogeneic hematopoietic stem cell transplant, photosensitivity, ocular pain, autologous eye drops, patient counseling, formulation, eye dryness

Related Categories: FORMULATIONS, OPHTHALMICS, PATIENT EDUCATION, CASE REPORTS, ALLERGY/IMMUNOLOGY/INFLAMMATION, DOSAGE FORMS/DRUG CARRIERS

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