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Proton Pump Inhibitor Homogenous Suspensions: A Compounding Solution to Pediatric Gastroesophageal Reflux Disease

Author(s):  Corsini Lindsay, Williams LaVonn A

Issue:  Mar/Apr 2011 - Volume 15, Number 2
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Abstract:  In the pediatric patient, histamine2-receptor antagonists and/or proton pump inhibitors are recommended for effective therapy of gastroesophageal reflux disease. Proton pump inhibitors, a group of drugs whose main action is a pronounced and long-lasting reduction of gastric acid production, are more cost effective than histamine2-receptor antagonists because of long-term and enhanced treatment outcome. The compounding of proton pump inhibitors is an exacting procedure. Compounding pharmacists have the potential to provide optimal pharmacologic treatment of gastroesophageal reflux disease to a young population that requires special attention.

Related Keywords: Lindsay Corsini, PharmD, LaVonn A. Williams, gastroesophageal reflux disease, GERD, children, infants, proton pump inhibitors, formulations, lansoprazole, omeprazole, pantoprazole, oral liquid suspensions

Related Categories: FORMULATIONS, GASTROENTEROLOGY, PEDIATRICS

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